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Roxanne Khamsi s+2
presents Beyond Inheritance,
in conversation with Apoorva Mandavilli
at McNally Jackson s+6

A captivating exploration of the remarkable ways our DNA mutates over the course of our lives, with radical implications for the future of medicine

Our DNA is the indispensable set of instructions that guides our growth and vitality. The common misconception is that this molecular blueprint stays the same throughout our lives. In reality, the genetic makeup of our cells is continuously mutating, from the moment we are conceived until our last breath. The hidden changes that amass in our genomes can have a huge influence on our health.

In this groundbreaking book, science writer Roxanne Khamsi describes our bodies as active landscapes of mutation. She reveals how the forces of Darwinian evolution operate within our own tissues. The effects can be devastating, such as when mutant blood cells outcompete their normal counterparts and increase the risk of heart attacks. But mutations can also make our bodies more resilient: Liver cells with genetic changes seem to cope better with excess calories. And immune cells with remixed DNA can make more effective antibodies against the microbes that threaten us.

By letting go of the antiquated idea that every cell in a body has the same exact DNA, we can usher in a whole new era of medicine, including better vaccines and treatments that outsmart cancer. Beyond Inheritance will open your eyes to the immense genetic diversity that exists within you and its incredible potential to shape your well-being.

 


Roxanne Khamsi is a longtime science journalist and a contributing writer at The Atlantic. Her writing has appeared in a wide range of publications, including The Economist, WIRED and The New York Times. She has received numerous accolades for her work, including top awards from the American Medical Writers Association and Association of Health Care Journalists, and her reporting has been featured in The Best American Science and Nature Writing anthology series. She lives in Montreal.

Apoorva Mandavilli is a reporter for the New York Times, focusing on science and global health. Her work has been published in The Atlantic, Slate and the New Yorker online.

Event Details

Wednesday, April 29, 2026
7:00pm

Price
$5

Location
McNally Jackson Seaport
4 Fulton St
New York, NY 10038

 

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McNally Jackson Books

Books. Some 65 thousand of them. History. More than 200 years of it. NYC’s beloved McNally Jackson’s Seaport outpost spans two floors of the historic Schermerhorn Row building, built in 1811. Windows overlook the cobblestones and armchairs anchor each room. Browse the shelves. Bring the kids to explore the big children’s section. Chat to the McNally staff and find your next great read.

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